Position: Post-doctoral Fellow
Address: Department of Biochemistry and Molecular Biology, UMASS, Amherst, USA
Telephone: 413-658-8266
E-Mail: xushb@biochem.umass.edu
Birthdate: October 10, 1974, XinJiang, China
POSITIONS
Post-doctoral Fellow (March 2011 – Present)
Associate Professor (September 2008-March 2011)
School of Life Sciences, Lanzhou University (Lanzhou, China)
Research Scientist (1996-2002)
Xinjiang Altay District Agricultural Extension Center (Xinjiang, China)
EDUCATION
Ph. D. in Developmental Biology (2005-2008)
Institute of Botany, Chinese Academy of Sciences (Beijing, China)
Advisor: Dr. Tai Wang
Thesis Title: Proteomic analysis of seed and endosperm development in Oryza sativa L. ssp japonica
M.S. in Plant Genetics and Breeding (2002-2005)
Xinjiang Agricultural University (Xinjiang, China)
Advisor: Dr Bingde Dou
Thesis Title: Construction of Genetic Map by SSR Marker and Location QTL for Plant Height and Heading Time in Wheat
B. S. in Agronomy (1992-1996)
Tarim University (Tarim, China)
SCIENTIFIC RESEARCH EXPERIENCE:
2011 – Present Department of Biochemistry and Molecular Biology, UMASS, Amherst, USA
Project: Function and regulation of a key enzyme in nitric oxide metabolism: S-nitrosoglutathione reductase
2008 – 2011 School of Life Sciences, Lanzhou University, Lanzhou, China
Project: Microarray data analysis of BR transduction pathway and proteomic analysis of brs1 in Arabidopsis thaliana.
Responsible for: microarray data analysis of wild type and BR signaling transduction mutants: TCP1, BRI1, BAK1, and BRS1; proteomic analysis of differentially expressed genes in wild type, overexpressing lines and knockdown mutants of BRS1 using 2D-DIGE; analysis of BRS1 isoforms modifications using 2-DE, Western Blot and MS
2005 – 2008 Institute of Botany, Chinese Academy of Sciences, Beijing, China
Ph.D. dissertation project: Proteomic analysis of seed and endosperm development in rice.
Advisor: Dr. Tai Wang
Responsible for: Rice seed development characterization using stereo microscopes and SEM; protein extractions, 2-DE (or 2D-DIGE), MS/MSMS ; RT-PCR for characterization of key genes expression; cytological assays: ATP assay, H2O2 detection, etc.
2003 – 2005 China Agricultural University, Beijing, China
M.S. degree thesis project: Genetic map construction using molecular markers and QTL mapping for important agronomic characters in wheat.
Advisor: Dr. Qixin Sun
Responsible for: Screening the appropriate molecular markers displaying different appearance in parent lines and offspring genotyping (RILs); constructing the genetic map with MAPMAKER/EXP3.0 software; quantification of agronomically important traits (plant height, heading time etc) within the population and QTLs analysis using QTLMAPPER1.6 and QTLNetwork software.
1996 – 2002 Altay District Agricultural Extension Center, Xinjiang, China
Research Assistant: Crop introduction and wheat breeding.
Advisor: Professor Xincheng Han
Responsible for: Variety regionalization for wheat, soybean, sunflower and maize; wheat breeding and farmer training in agricultural technology.
GRANTS FUNDED
1, National Natural Science Foundation of China, 2010.01-2013.12, 90917019.
Title: ”The regulation function of TCP-like transcription factors in Brassinosteroid synthesis and signaling transduction”. Grant awarded to PI: Jia Li, Co-PI: Yurong Bi, Xiaoping Gou, and Shengbao Xu.
2, Lanzhou university, 2010.1-2010.12, lzujbky-2009-35. Principal Investigator: ShengBao Xu.
“Analysis of the Brassinosteroid regulatory network and crosstalk with other plant hormones”.
PUBLICATIONS
Hua Tao Yu, Sheng Bao Xu, Can Hui Zheng and Tai Wang (2011) Comparative Proteomic Study Reveals the Involvement of Diurnal Cycle in Cell Division, Enlargement, and Starch Accumulation in Developing Endosperm of Oryza sativa. Journal of Proteome Research publish on line Novmber, 2011 DOI: 10.1021/pr200779p
Gang Liu, ShengBao Xu, ZhongFu Ni, ChaoJie Xie, DanDan Qin, Jing Li, LaHu Lu, JinPing Zhang, HuiRu Peng and QiXin Sun (2011) Molecular dissection of plant height QTLs using recombinant inbred lines from hybrids between common wheat (Triticum aestivum L.) and spelt wheat (Triticum spelta L.) Chinese Science Bulletin 56(18), 1897-1903
Xu SB, Hua Tao Yu, Long Feng Yan, Tai Wang (2010) Integrated proteomic and cytological study of rice endosperms at the storage phase. Journal of Proteome Research 9 (10), pp 4906–4918.
Xu SB, Li T, Deng ZY, Chong K, Xue Y, Wang T (2008) Dynamic proteomic analysis reveals a switch between central carbon metabolism and alcoholic fermentation in Oryza sativa filling grains. Plant Physiology 148(2): 908-925 (Recommended by Faculty of 1000 biology).
Zhao LF, Xu SB, Chai T, Wang T (2006) OsAP2-1, an AP2-like gene from Oryza sativa, is
required for flower development and male fertility. Sexual Plant Reproduction 19: 197-206.
CONFERENCE PRESENTATIONS
18th International Conference on Arabidopsis Research, 2007, Beijing, China
ASPB Annual Meeting, 2011, GSNOR: An enzyme of nitric oxide metabolism is essential to normal growth and stress responses in plants, Minneapolis, Minnesota, USA
EXPERIENCE IN EDUCATION
Student Supervision (2009-2010)
Responsible for training PhD candidates in microarray analysis and MS students in proteomics.
Tutoring (2009-2010)- Undergraduate Level Biochemistry Course.
OTHER PROFESSIONAL ACTIVITIES
Reviewer for “Acta Agronomica Sinica” and “Journal of Tropical and Subtropical Botany”