UMass Scientists Make Bigger Tomatoes!
UMass student Jarrett Man and Prof. Madelaine Bartlett are doing important work in the agricultural field.
Engineering Quantitative Trait Variation for Crop Improvement by Genome Editing
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Zachary B. Lippman3,
Correspondence information about the author Zachary B. Lippman
Email the author Zachary B. Lippman
Correspondence information about the author Zachary B. LippmanEmail the author Zachary B. Lippman3Lead Contact
Highlights
- CRISPR/Cas9 targeting of a cis-regulatory motif recreated a domestication QTL
- CRISPR/Cas9 drove mutagenesis of promoters to create a continuum of variation
- Phenotypic effects were not predictable from allele type or transcriptional change
- Selected promoter alleles in developmental genes could improve yield traits
